ACTA NEUROPHARMACOLOGICA ›› 2020, Vol. 10 ›› Issue (6): 34-40.DOI: 10.3969/j.issn.2095-1396.2020.06.006

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Advances in Pharmacological Effects of Chrysophanol

YUAN Xin-ru, ZHANG Dan-shen   

  1. Hebei University of Science and Technology, Shijiazhuang, 050000, China
  • Online:2020-12-26 Published:2020-12-26
  • Contact: 张丹参,女,博士生导师;研究方向:神经药理学;Tel:+86-0311-81668016,E-mail:zhangds2011@126.com
  • Supported by:
    河北省重点研发计划项目生物医药专项(No.20372509D);河北省自然科学基金(No.H2020208032);河北省高等学校科学技术研究项目(No.ZD2020117);河北省中医药管理局中医药科研计划项目(No.2020268);中央财政公共卫生专项“中药资源普查项目”(No.Z135080000022)

Abstract:

Chrysophanol is one of the effective monomers of anthraquinones that extracted from traditional Chinese medicine. It exists in the form of free aglycon in rhubarbfleeceflower rootpolygonum cuspidatumcassiapinelliaetc. Studies have found that chrysophanol has good pharmacological activities in neuroprotectionanti-oxidationanti-canceranti-inflammatoryantibacterial and anti-virusand promotion of fat metabolism. Although there are many studies on the pharmacological activity of chrysophanolthe overall review of it is relatively few. This article provides a comprehensive review of the pharmacological effects of chrysophanoland provides valuable references for further research and clinical applications.

Key words: Chrysophanol, neuroprotection, antioxidant, anti-cancer, anti-inflammatory

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