The Relationship between Cytokines and Depression

doi:10.3969/j.issn.2095-1396.2016.04.005

Abstract

Abstract: Depression is one of the most prevalent psychiatric diseases characterized by a state of low mood，cognitive disorders. Increasing studies have showed that chronic stress activates peripheral and central immune systems accompanied with the release of cytokines（including proinflammatory and anti-inflammatory cytokines），which play a significant role in the pathogenesis of depression. The objective of this review is to discuss the underlying mechanisms between cytokines （including proinflammatory and anti-inflammatory cytokines） and depressive disorders.

Key words: depression, cytokine, pro-inflammatory cytokine, anti-inflammatory cytokine

ZHANG Xiao-ling，WANG Zhen-zhen，WEN Lu，SHAO Qian-hang，CHEN Nai-hong. The Relationship between Cytokines and Depression[J]. Acta Neuropharmacologica, 2016, 6(4): 31-36.

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