Analysis of Animal Models of Depression Based on Clinical Symptoms

doi:10.3969/j.issn.2095-1396.2016.04.003

Abstract

Abstract: Objective：To analyze the characteristics of the existing animal models and the accordance with the clinical symptoms based on the clinical symptoms of Chinese and Western medicine in depression. Methods：Through combing the related literatures at home and abroad in recent years，we compared and analyzed the characteristics of depression，clinical symptoms and the more modern depression model. Results：The detection of symptoms，most of the existing concept of animal models of depression observed the biochemical indicators and clinical symptoms，the main index of agreement is relatively high，a few animal models are consistent with clinical symptoms is relatively low. Conclusion：The animal models of depression should be improved according to the characteristics of clinical diseases，which will be closer to the characteristics of human diseases in the etiology，pathogenesis and disease characteristics，and provide more reliable experimental support for the clinical.

Key words: clinical characteristics of the disease, depression, animal model, anastomosis

CAO Li-hua，BAI Ming，FANG Xiao-yan，WANG Can，MIAO Ming-san. Analysis of Animal Models of Depression Based on Clinical Symptoms[J]. Acta Neuropharmacologica, 2016, 6(4): 19-23.

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