Research Progress of SIRT1 in Cerebral Ischemia-Reperfusion Injury

doi:10.3969/j.issn.2095-1396.2020.06.007

ACTA NEUROPHARMACOLOGICA ›› 2020, Vol. 10 ›› Issue (6): 41-44.DOI: 10.3969/j.issn.2095-1396.2020.06.007

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Research Progress of SIRT1 in Cerebral Ischemia-Reperfusion Injury

ZHANG Jia-xiu，ZOU Yu-an

1. Graduate School of Hebei North University，Zhangjiakou，075000，China
2. Department of Neurology, the First Affiliated Hospital of Hebei North University，Zhangjiakou，075000，China

Online:2020-12-26 Published:2020-12-26
Contact: 邹玉安，男，主任医师，硕士研究生导师;E-mail:baiyitiansho@163.com
About author:张佳秀，女，河北北方学院研究生学院;研究方向:神经病学;E-mail:zjxiu1993@163.com

Abstract

Abstract:

Acute ischemic stroke is a kind of disease with complicated pathogenesis and no effective treatment at present. Silencing information regulator 1(SIRT1)is a nicotinamide adenine dinucleotide(NAD+)-dependent deacetylase，and is one of the important regulators of aging，apoptosis and other physiological activities. Studies have shown that SIRT1 is closely related to the neuroprotective effect of cerebral ischemia-reperfusion injury and may be a new target for the treatment of acute ischemic stroke.

Key words:

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CLC Number:

ZHANG Jia-xiu, ZOU Yu-an.

Research Progress of SIRT1 in Cerebral Ischemia-Reperfusion Injury [J]. ACTA NEUROPHARMACOLOGICA, 2020, 10(6): 41-44.

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Research Progress of SIRT1 in Cerebral Ischemia-Reperfusion Injury

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