神经药理学报 ›› 2013, Vol. 3 ›› Issue (2): 43-48.

• 专题论著 • 上一篇    下一篇

下尿路神经功能的研究方法与模型及其评价

吴志刚, 沈丽霞   

  1. 河北北方学院药学系,张家口,075000,中国
  • 出版日期:2013-04-26 发布日期:2014-06-27
  • 通讯作者: 沈丽霞,女,教授;研究方向:神经药理学;Tel:+86-0313-4029305,E-mail:shenlixiacn@sina.com
  • 作者简介:吴志刚,男,讲师;研究方向:神经药理学;Tel:+86-0313-4029305,E-mail:wuzhigang1982@126.com
  • 基金资助:

    河北省教育厅项目(No. Z2012014),河北北方学院校级课题项目(No. Q2013028)

Evaluation of Methods and Models on Lower Urinary Tract Nerve Function

WU Zhi-gang, SHEN Li-xia   

  1. Department of Pharmacy, Hebei North University, Zhangjiakou, 075000, China
  • Online:2013-04-26 Published:2014-06-27
  • Contact: 沈丽霞,女,教授;研究方向:神经药理学;Tel:+86-0313-4029305,E-mail:shenlixiacn@sina.com
  • About author:吴志刚,男,讲师;研究方向:神经药理学;Tel:+86-0313-4029305,E-mail:wuzhigang1982@126.com
  • Supported by:

    河北省教育厅项目(No. Z2012014),河北北方学院校级课题项目(No. Q2013028)

摘要: 下尿路的神经控制是一个极为复杂的神经回路,涉及到特定的外周神经以及不同水平中枢神经系统。下尿路功能障碍是临床常见疾患,多年来通过动物实验和临床研究积累了大量有关下尿路神经功能的资料。本文以研究膀胱、尿道神经功能的实验方法和模型研究为切入点,综述相关研究报道,以期为下尿路功能障碍的基础研究和临床防治研究提供较为全面的技术资料。

关键词: 下尿路, 膀胱, 尿道, 动物模型

Abstract: Control of the lower urinary tract requires complex neuronal circuits that involve elements located at the peripheral nervous system and at different levels of the central nervous system. The lower urinary tract dysfunction is a clinical common disease. Through animal experiments and clinical research, we have accumulated much information of related lower urinary tract nerve function for years. In this paper,we take the bladder, urethra tract nerve function experiment method and model research as the breakthrough point, and try to provide comprehensive technical information for the the basic research and clinical prevention and treatment research of the urinary tract dysfunction,through reviewing related research reports.

Key words: lower urinary tract, Bladder, urethra, animal models