诱发支气管哮喘动物模型方法及评价

doi:10.3969/j.issn.2095-1396.2019.04.001

摘要/Abstract

摘要：

支气管哮喘是呼吸系统疾病中的一种慢性气管变态反应炎症性疾病，由于哮喘病因非常复杂，其发病机制至今尚不十分清楚，许多研究需要通过动物模型进行。该文对诱发哮喘动物模型中动物的性别，体质量，用药量，方法等进行详述，为哮喘机制研究以及哮喘预防和治疗提供基础资料，为进一步开展哮喘相关研究提供帮助。

关键词: 哮喘, 动物模型, 制备方法, 评价

Abstract:

Bronchial asthma is a chronic tracheal allergic inflammatory disease in respiratory diseases. Because the cause of asthma is very complicated，its pathogenesis is still not fully understood，and many studies need to be carried out through animal models. This paper details the sex，body weight dosage，and methods，ect. of animals in an animal model of induced asthma. Provides basic information for asthma mechanism research and asthma prevention an treatment，and provides assistance for further research on asthma.

Key words: asthma, animal models, preparation methods, evaluation

中图分类号:

R332

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张丹参，张楠. 诱发支气管哮喘动物模型方法及评价[J]. 神经药理学报, DOI: 10.3969/j.issn.2095-1396.2019.04.001.

ZHANG Dan-shen，ZHANG Nan. Methods and Evaluation of Animal Models of Induced Bronchial Asthma[J]. Acta Neuropharmacologica, DOI: 10.3969/j.issn.2095-1396.2019.04.001.

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