雌激素及其受体与高血压相关性疾病的研究进展

神经药理学报 ›› 2013, Vol. 3 ›› Issue (3): 34-38.

雌激素及其受体与高血压相关性疾病的研究进展

马新喆，吕洋，王海萍

河北北方学院，张家口， 075000，中国

出版日期:2013-06-26 发布日期:2014-06-27
通讯作者: 王海萍，女，教授，硕士生导师；E-mail: haipingmimi@126.com
作者简介:马新喆，学士，临床医学；E-mail :1186785729@qq.com
基金资助:
河北北方学院重大科研项目（No.ZD201316）

A Review on the Relationship between Estrogen, Estrogen Receptor and Hypertension Disease

MA Xin-zhe ，LV Yang，WANG Hai-ping

Hebei North University, Zhangjiakou, 075000, China

Online:2013-06-26 Published:2014-06-27
Contact: 王海萍，女，教授，硕士生导师；E-mail: haipingmimi@126.com
About author:马新喆，学士，临床医学；E-mail :1186785729@qq.com
Supported by:
河北北方学院重大科研项目（No.ZD201316）

摘要/Abstract

摘要： 雌激素是由胎盘及卵巢产生的类固醇性激素。雌激素受体(ER)属于核受体超级家族成员，具有广泛的组织分布，为雌激素发挥作用提供了保证。研究表明雌激素及其受体的生物学效应对心血管疾病特别是高血压疾病密切相关。现将雌激素及雌激素受体对高血压疾病的作用机制及研究进展进行综述。

关键词: 雌激素, 雌激素受体, 高血压

Abstract: Estrogen is a steroid hormone, which is produced by the placenta and ovaries. Estrogen receptor (ER) belongs to the nuclear receptor superfamily, which is widely expressed in tissues. Studies have shown that estrogen and estrogen receptors’ biological effects are closely related to the function of cardiovascular system, especially for hypertension. The article will summarize the research progress and the mechanism of action of estrogen and its receptors in their involvement in hypertension .

Key words: estrogen, estrogen receptor, hypertension

马新喆, 吕洋, 王海萍. 雌激素及其受体与高血压相关性疾病的研究进展[J]. 神经药理学报, 2013, 3(3): 34-38.

MA Xin-zhe, LV Yang, WANG Hai-ping. A Review on the Relationship between Estrogen, Estrogen Receptor and Hypertension Disease[J]. ACTA NEUROPHARMACOLOGICA, 2013, 3(3): 34-38.

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