ACTA NEUROPHARMACOLOGICA

Acta Neuropharmacologica ›› 2017, Vol. 7 ›› Issue (4): 31-35.DOI: 10.3969/j.issn.2095-1396.2017.04.005

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The Research Progress of Plasma Lipoprotein-associated Phospholipase A2 and Ischemic Stroke

PANG Xue-bo，XUE Qian，ZOU Yu-an   

  1. 1. Hebei North University，Zhangjiakou，075000，China
    2. Department of Neurology，the First Affiliated Hospital of Hebei North University，Zhangjiakou，075000，China
  • Online:2017-08-26 Published:2017-12-01
  • Contact: 薛茜，女，主任医师，教授，硕士研究生导师；研究方向：缺血性脑血管病
  • About author:庞学波，男，硕士研究生；研究方向：缺血性脑血管病；E-mail：843018688@qq.com

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Abstract: It is known that atherosclerosis is the pathological basis of ischemic cerebral apoplexy. A large number of studies suggest that plasma lipoprotein-associated phospholipase A2（Lp-PLA2）， as a new inflammation factor，plays a role in the development of atherosclerosis， and it is a independent risk factor for cardiovascular and cerebrovascular disease. This review summarizes the relationship between Lp-PLA2 and the ischemic stroke.

Key words: plasma lipoprotein-associated phospholipase A（2 Lp-PLA2）, atherosclerosis , ischemic stroke

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