[ ] Renee Van Aerongen, Roel Nusse. Towards an integrated view of Wnt signal in development [J]. Development, 2009, 136(19): 3205-3214.[ ] Clevers Hans, Nusse Roel. Wnt/β-catenin signaling and disease [J]. Cell, 2012, 149(6):1192-1205.[3] Choi Hyun-Jung, Park Hongryeol, Lee Heon-Woo, et al. The Wnt pathway and the roles for its antagonists, DKKS, in angiogenesis [J]. IUBMB Life, 2012, 64(9):724-731.[ ] Dejana Elisabetta, Tournier–Lasserve Elisabeth, Weinstein Brant M. The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications[J]. Dev Cell, 2009, 16(2): 209-221.[ ] Huelsken J. Canonical Wnt signaling plays essential roles [J]. Eur J Immunol, 2009, 39(12): 3582-3583.[6] Yang Ying-zi. Wnt signaling in development and disease [J]. Cell Biosci, 2012, 2(1):14.[7]Jennifer L Green, Inoue Takao, Paul W Sternberg. The C. elegans ROR receptor tyrosine kinase, CAM–1,non-autonomously inhibits the Wnt pathway[J]. Development, 2007, 134(22):4053-4062.[8] Carmeliet Peter, Rakesh K Jain. Molecular mechanisms and clinical applications of angiogenesis[J]. Nature, 2011, 473(7347):298-307.[9] John J Ohab, Sheila Fleming, Armin Blesch, et al. A neurovascular niche for neurogenesis after stroke[J].J Neurosci, 2006, 26(50):13007-16.[10] Maretto Silivia, Cordenonsi Michelangelo, Dupont Sirio, et al. Mapping Wnt/beta–catenin signaling during mouse development and in colorectal tumors[J]. Proc Natl Acad Sci USA, 2003, 100(6):3299-3304.[11] Goodwin Anne, Sullivan Kaitlyn, D’Amore Patricia. Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling [J]. Dev Dyn, 2006, 235(11):3110-3120.[12] T Nestor H Masckauchan, Drian Agalliu, Marina Vorontchikhina et al. Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP–1 and Tie–2[J]. Mol Biol Cell, 2006, 17(12):5163-5172. [13] de Jesus Perez Vinicio A, Alastalo Tero-Pekla, Wu Jenny C, et al. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways[J]. J Cell Biol, 2009, 184(1):83-99. [14] Phng LK, Potente M, Leslie JD, et al. Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis[J]. Dev Cell, 2009, 16(1):70-82. [15] Goodwin Anne M, Kitajewski Jan, D’Amore Patricia. Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not[J]. Growth Factors, 2007, 25(1):25-32. [16] Benedito Rui, Roca Cristina, Sorensen Inga, et al. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis[J]. Cell, 2009, 137(6):1124-1135. [17] Aviel-Ronen Sarit, Blackhall Fiona H, Shepherd Frances A, et al. K-ras mutations in non-small-cell lung carcinoma:A review[J]. Clin Lung Cancer, 2006, 8(1):30-38. [18] Daneman Richard,Aqulliu Dritan,Zhou Lu. Wnt/β-catenin signaling is required for CNS, but not non-CNS, angiogenesis[J]. Proc Natl Acad Sci USA, 2009, 106(2):641-646.[19] Anderson Keith D, Pan Li, Yang Xiao-Man, et al. Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor[J]. Proc Natl Acad Sci USA, 2011, 108(7):2807-2812.[20] Griffin Courtney T, Curtis Carol D, Davis Reema B, et al. The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels[J]. Proc Natl Acad Sci USA, 2011, 108(6):2282-2287.[21] Takahashi Tetsuya, Steinberg Gary K, Zhao Heng. Lithium treatment reduces brain injury by focal ischemia with partial reperfusion and the protective mechanisms dispute the importance of akt activity[J]. Aging Dis, 2012, 3(3):226-233.[22] Guo Shu-zhen, Arai Ken, Stins Monique F, et al. Lithium upregulates vascular endothelial growth factor in brain endothelial cells and astrocytes[J]. Stroke, 2009, 40(2):652-655.[23] Prinz V, Endres M. Statins and stroke:prevention and beyond[J].Curr Opin Neurol, 2011, 24(1):75-80.[24] Hoang Stanley, Liauw Jason, Choi Matthew, et al. Netrin-4 enhances angiogenesis and neurologic outcome after cerebral ischemia[J].J Cereb Blood Flow Metab, 2009, 29(2):385-397.[25] Ling Li, Hou Qing-hua, Xing Shi-hui, et al. Exogenous kallikrein enhances neurogenesis and angiogenesis in the subventricular zone and the peri-infarction region and improves neurological function after focal cortical infarction in hypertensive rats[J].Brain Res, 2008, 1206:89-97. |