ACTA NEUROPHARMACOLOGICA ›› 2020, Vol. 10 ›› Issue (4): 41-50.DOI: 10.3969/j.issn.2095-1396.2020.04.008

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Research Progress of Signal Pathways in Drug Treatment of Ulcerative Colitis

GUO Zi-xia,AN Zi-xuan,ZHANG Jian-mei,ZHANG Dan-shen   

  1. 1. Department of Pharmacy,Hebei North University,Zhangjiakou,075000,China
    2. Hebei University of Science and Technology,Shijiazhuang,050018,China
  • Online:2020-08-26 Published:2020-08-26
  • Contact: 张丹参,教授,博士,博士生导师;研究方向:神经药理学;E-mail:zhangds2011@126.com
  • About author:郭子霞,硕士研究生;研究方向:药理学;E-mail:2389707795@qq.com
  • Supported by:
    河北省重点研发计划项目生物医药专项(No.20372509D);河北省自然科学基金(No.H2020208032);河北省高等学校科学技
    术研究项目(No.ZD2020117);河北省中医药管理局中医药科研计划项目(No.2020268);中央财政公共卫生专项“中药资源普
    查项目”(No.Z135080000022)

Abstract:

Ulcerative colitis (UC) is a disease affected by multiple factors and is prone to repeated attacks. It is one of the most intractable diseases recognized in the world. The effect of current drug treatment is not good,so people pay more and more attention to it. This article mainly reviews the signal pathways related to UC pathogenesis and the effects of therapeutic drugs,to provide more reference for future research on new drugs or new mechanisms,and to classify and evaluate the modeling methods of animal models used in experiments,in order to provide references for researchers to choose suitable models.

Key words: ulcerative colitis, modeling method, medication, signal pathway

CLC Number: