Acta Neuropharmacologica

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The Establishment and Evaluation of Animal Models of Neuropathic Pain

WU Ya-ru,CHANG Ke-xin,JIA Qing-zhong   

  1. Hebei Medical University,Shijiazhuang,050017,China
  • Online:2017-10-26 Published:2017-12-01
  • Contact: 贾庆忠,男,教授,硕士生导师;研究方向:神经药理学;Tel:+86-0311-86265644,E-mail:qizhjia2000@sina.com
  • About author:武亚茹,女,硕士研究生;研究方向:神经药理学;E-mail:15369312998@163.com
  • Supported by:
    国家自然科学基金资助项目(No.30970659),河北省高层次人才项目(No.2014038)

Abstract: Neuropathic pain can be defined as “pain arising as a direct consequence of a lesion or disease affecting the somato-sensory system”. This article reviews animal models of neuropathic pain induced by peripheral nerve injury,herpes zoster,diabetes and cancer and its evaluation methods.

Key words: neuropathic pain, animal model, allodynia, hyperalgesia

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