ACTA NEUROPHARMACOLOGICA

ACTA NEUROPHARMACOLOGICA ›› 2023, Vol. 13 ›› Issue (2): 46-.DOI: 10.3969/j.issn.2095-1396.2023.02.008

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Research Progress on the Involvement of Bile Acids in the Pathogenesis of Chronic Atrophic Gastritis and Its Intervention with Traditional Chinese Medicine

LU Wen-tian，QIN Xue-mei，LIU Yue-tao   

  1. 1.Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, 030006, China

    2.Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Taiyuan, 030006, China

    3.Shanxi Key Laboratory of Active Constituents Research and Utilization of TCM, Taiyuan, 030006, China

  • Online:2023-04-26 Published:2023-11-30

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Abstract:

Bile acid (BA) is involved in the development of chronic atrophic gastritis through a variety of mechanisms when it refluxes into the stomach under certain pathological conditions. This article reviews its involvement in the pathogenesis of chronic atrophic gastritis and its herbal treatment, with a view to providing new ideas for the study and treatment of chronic atrophic gastritis and bile reflux-related gastric diseases.

Key words: bile acid, chronic atrophic gastritis, gastric mucosa, gastric flora, traditional Chinese medicine intervention