Research Progress in Pharmacological Activities of Ginsenoside-Rg3

doi:10.3969/j.issn.2095-1396.2017.01.005

Abstract

Abstract: Ginseng is a traditional Chinese drug，with a long medicinal history. The main active components of ginseng are the ginsenosides，among which the ginsenoside-Rg3 is a kind of components in ginseng，with higher medicinal value，studying on the pharmacological effects can provide theoretical guidance for further development and utilization of ginsenoside-Rg3. According to domestic and foreign researches reports of ginsenoside-Rg3 in recent years，the pharmacological effects of ginsenoside-Rg3 were summarized and analyzed in this review. The pharmacological studies reported in the literature have indicated that the ginsenoside-Rg3 exhibited various pharmacological activities，such as anti-tumor，reduce the cardiac toxicity and nephrotoxicity of chemotherapy drugs，reverse the multidrug resistance of tumor cells to anticancer drugs，protect the central nervous system and cardiovascular system，anti-fatigue，hypoglycemic effect，repair wound，and other aspects.

Key words: ginsenoside-Rg3, pharmacological activitiy, anti-tumor, central nervous system, cardiovascular system

CLC Number:

R932

SU Xiao-mei，ZHANG Dan-shen. Research Progress in Pharmacological Activities of Ginsenoside-Rg3[J]. Acta Neuropharmacologica, 2017, 7(1): 38-44.

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