Acta Neuropharmacologica ›› 2011, Vol. 1 ›› Issue (2): 35-41.

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Methods and Evaluation of Animal Models of Induced Cough

ZHANG Dan-shen   

  1. Department of Pharmacy,Hebei North University,Zhangjiakou,075000,China
  • Online:2011-04-26 Published:2012-04-20

Abstract: The cough induced by many factors is a common symptom of a variety of respiratory diseases. Ideal animal models are needed not only for the studies on the incidence and control mechanisms of the cough reflex, and etiology and pathogenesis of the cough, but also for the research and development of effective antitussives and the treatment of human cough. In this review, the animal models of induced cough were described in detail and evaluated to provide some guidance for related basic and clinical research and applications.

Key words: cough, animal models, preparation methods, evaluation

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