Acta Neuropharmacologica

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Advances in Research on Modern Pharmacological Effects and Clinical Application of Cnidium

SONG Yi-lei,HOU Xue-qin,HAO Ji-fu   

  1. Shandong First Medical University & Shandong Academy of Medical Sciences,Taian,271016,China
  • Online:2019-12-26 Published:2020-03-03
  • Contact: 郝吉福,教授,硕士生导师;研究方向:药物新剂型与新技术; E-mail:15864769568@163.com
  • About author:宋宜蕾,女,药剂学硕士研究生; E-mail:15621339326@163.com
  • Supported by:
    国家自然科学基金项目(No.81703901),山东省重点研究项目(No.2019GSF108069),山东省中医药管理局项目(No.2019-0361)

Abstract:

Cnidium is a dry and mature fruit of the genus Umbelliferae. It is a traditional Chinese medicinal material. It has been recorded in ancient history books. It is mainly used in clinical practice and is mainly used for the treatment on gynecology and surgery. For diseases such as dermatology,male diseases are mainly based on internal medicine. Cnidium contains a variety of chemical components,mainly containing coumarins,volatile oils,sugars and various trace elements. Osthole is one of the main components of the effect of Cnidium. Modern pharmacological studies have found that osthole has therapeutic effects on diseases such as cardiovascular and cerebrovascular system,central nervous system,endocrine system and immune system.

Key words: cnidium, chemical composition, osthole, pharmacological action, mechanism

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