帕金森病患者下尿路功能障碍的治疗进展

神经药理学报 ›› 2014, Vol. 4 ›› Issue (4): 36-41.

帕金森病患者下尿路功能障碍的治疗进展

吴志刚，沈丽霞

河北北方学院药学系，张家口，075000，中国

出版日期:2014-08-26 发布日期:2015-01-20
通讯作者: 沈丽霞，女，教授；研究方向：神经药理学；Tel：+86-0313-4029305，E-mail：shenlixiacn@sina.com
作者简介:吴志刚，男，讲师；研究方向：神经药理学；Tel：+86-0313-4029305，E-mail：wuzhigang1982@126.com
基金资助:
河北省教育厅项目（No. Z2012014），河北北方学院校级课题项目（No. Q2013028）

Treatment for Lower Urinary Tract Dysfunction in Patients with Parkinson’s Disease

WU Zhi-gang，SHEN Li-xia

Department of Pharmacy, Hebei North University, Zhangjiakou, 075000, China

Online:2014-08-26 Published:2015-01-20
Contact: 沈丽霞，女，教授；研究方向：神经药理学；Tel：+86-0313-4029305，E-mail：shenlixiacn@sina.com
About author:吴志刚，男，讲师；研究方向：神经药理学；Tel：+86-0313-4029305，E-mail：wuzhigang1982@126.com
Supported by:
河北省教育厅项目（No. Z2012014），河北北方学院校级课题项目（No. Q2013028）

摘要/Abstract

摘要： 帕金森病是一种渐进的中枢神经系统退行性疾病。尽管帕金森病是以运动症状为主要特征，但其非运动症状也逐渐受到重视。帕金森病患者常常会出现下尿路功能障碍，主要症状包括尿急、尿频、夜尿症、急迫性尿失禁等，严重影响患者的生活质量。本文综述目前临床常用的治疗策略以及一些潜在的治疗方法，希望这些治疗能够最大限度地提高患者的生活质量。

关键词: 帕金森病, 治疗, 下尿路, 膀胱, 尿道, 功能障碍

Abstract: Parkinson’s disease is a progressive degenerative disorder of the central nervous system. Although motor symptoms are a predominant feature of the condition, non-motor symptoms have also been recognized. Lower urinary tract dysfunction is frequently present in patients affected with Parkinson’s disease. Symptoms such as urgency, frequency, nocturia and urge incontinence significantly impact the patient’s quality of life. We present an overview of current and prospective treatment strategies. These treatments might be beneficial in maximizing the patients’ quality of life.

Key words: Parkinson&, rsquo, s disease, treatment, lower urinary tract, bladder, urethra, dysfunction

中图分类号:

R964

吴志刚，沈丽霞. 帕金森病患者下尿路功能障碍的治疗进展[J]. 神经药理学报, 2014, 4(4): 36-41.

WU Zhi-gang，SHEN Li-xia. Treatment for Lower Urinary Tract Dysfunction in Patients with Parkinson’s Disease[J]. Acta Neuropharmacologica, 2014, 4(4): 36-41.

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