睡眠影响记忆巩固的研究进展

摘要/Abstract

摘要： 学习后睡眠有利于记忆巩固。学习的类型不同，睡眠依赖的记忆巩固机制可能也有所不同，涉及到不同脑区在不同的睡眠时相的生理功能。睡眠有助于长时程增强（long-term potentiation，LTP）的形成，进而促进记忆的巩固。总睡眠剥夺、快动眼睡眠剥夺、片段性睡眠可以通过不同的分子生物学机制损伤记忆巩固。

关键词: 睡眠, 学习, 记忆, 脑电图, 长时程增强

Abstract: Delayed post learning sleep but not wakefulness enhances memory consolidation. Different types of learning have unique sleep-related memory consolidation mechanisms that act in dissociable brain regions during different sleep phases throughout the night. Sleep exerts beneficial effect on memory consolidation by improving formation of long-term potentiation. Total sleep deprivation, rapid eye movement sleep deprivation and sleep fragmentation may lead to memory deficits through different molecular mechanisms.

Key words: sleep, learning, memory, electroencephalography, long-term potentiation

盛兆福，张永鹤. 睡眠影响记忆巩固的研究进展[J]. 神经药理学报, 2013, 3(1): 37-47.

SHENG Zhao-fu, ZHANG Yong-he. Effect of Sleep on Memory Consolidation[J]. Acta Neuropharmacologica, 2013, 3(1): 37-47.

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