Progress in Understanding the Mechanism of Protective Effects of Cerebral Ischemia Injury

Abstract

Abstract: Cerebral ischemic disease is a common disease clinically, and frequently-occurring disease. Research shows that there is serious harm after cerebral ischemia reperfusion injury. In recent years, the cerebral ischemia reperfusion protection was laid emphasis on by the international medical circles. It is very significant for the protective mechanism of further research of cerebral ischemia injury, the discovery of cerebral ischemic disease treatment targets, and the development of the corresponding drugs. This review was focused on the research progress in understanding the mechanism of protective effects of cerebral ischemia injury.

Key words: cerebral ischemic injury, oxygen radical, inflammatory response, excitatory amino acid, apoptosis, heat stock protein, ischemical preconditioning, mild hypothermia

CLC Number:

R964

ZHAO Wei, LI Fang-jiang, WANG Shu. Progress in Understanding the Mechanism of Protective Effects of Cerebral Ischemia Injury[J]. Acta Neuropharmacologica, 2014, 4(6): 55-64.

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