神经药理学报 ›› 2012, Vol. 2 ›› Issue (3): 52-64.
• 综述 • 上一篇
张思1，王烁宇2， 李华南3， 张国福3， 顾兵1
出版日期:2012-06-26
发布日期:2013-12-25
通讯作者:
顾兵，男，博士后，教授，硕士生导师；研究方向：神经精神药物学；E-mail: bguemory@hotmail.com
作者简介:张思，女，江西科技师范大学化学生物学硕士研究生；E-mail：847404553@qq.com
基金资助:国家自然科学基金资助项目（No.30960448），江西省自然科学基金项目（No.20114BAB205033），江西省教育厅科技项目（No.GJJ11596）
ZHANG Si1, WANG Shuo-yu2, LI Hua-nan3, ZHANG Guo-fu3, GU Bing1
Online:2012-06-26
Published:2013-12-25
Contact:
顾兵，男，博士后，教授，硕士生导师；研究方向：神经精神药物学；E-mail: bguemory@hotmail.com
About author:张思，女，江西科技师范大学化学生物学硕士研究生；E-mail：847404553@qq.com
Supported by:国家自然科学基金资助项目（No.30960448），江西省自然科学基金项目（No.20114BAB205033），江西省教育厅科技项目（No.GJJ11596）
摘要： 急性脊髓损伤可导致严重的运动、感觉功能障碍。由自由基引起的氧化应激在继发性损伤的病理生理过程中占有重要地位。通过有效的抗氧化干预抑制损伤后生物大分子的过氧化反应，将成为药物治疗脊髓损伤的一条策略。本文主要介绍氧化应激的产生原因、作用过程和参与急性脊髓损伤的病理生理机制，并综述抗氧化药物实验研究最新进展，旨在为寻找安全有效的药物提供参考依据。
中图分类号:
张思，王烁宇， 李华南， 张国福， 顾兵. 急性脊髓损伤后的氧化应激及其抗氧化治疗[J]. 神经药理学报, 2012, 2(3): 52-64.
ZHANG Si, WANG Shuo-yu, LI Hua-nan, ZHANG Guo-fu, GU Bing. Oxidative Stress and Antioxidant Therapy after Acute Spinal Cord Injury[J]. Acta Neuropharmacologica, 2012, 2(3): 52-64.
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