Research Advance in Relationship between Adult Hippocampal Neurogenesis and Mechanisms of Depression

Abstract

Abstract: Adult hippocampal has continuous neurogenesis, early studies have found that adult neurogenesis is impaired in models of depression. In this review, we will analyze the current studies on the relationship between depression and adult hippocampal neurogenesis as follows: image changes in depression patients, relationship between hippocampal neurogenesis and depression, and antidepressant effects on neurogenesis.

Key words: depression, hippocampal, neurogenesis, dentate gyrus

Jin Can, ZHANG Dan-shen, CHEN Nai-hong. Research Advance in Relationship between Adult Hippocampal Neurogenesis and Mechanisms of Depression[J]. Acta Neuropharmacologica, 2013, 3(2): 58-64.

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