神经药理学报

• 研究论文 •    下一篇

苏艾冰精油外用对小鼠抗缺氧能力的影响

魏珍珍 方晓艳 白 明 苗明三 樊帅珂   

  1. 河南中医药大学,郑州,450046,中国
  • 出版日期:2019-10-26 发布日期:2020-03-03
  • 通讯作者: 苗明三,男,教授,博士;研究方向:主要从事中药药理教学与研究;E-mail:miaomingsan @163.com
  • 作者简介:魏珍珍,女,硕士研究生;研究方向:中药药理学;E-mail:weizhenzhen08@126.com
  • 基金资助:
    国家中医药管理局中医药标准化专项项目(No.2017-149-11),河南省产学研合作项目(No.182107000029)

Effects of Suaibing Essential Oil on Anti-Hypoxia Ability of Mice

WEI Zhen-zhen,FANG Xiao-yan,BAI Ming,MIAO Ming-san,FAN Shuai-ke   

  1. Henan University of Chinese Medicine,Zhengzhou,450046,China
  • Online:2019-10-26 Published:2020-03-03
  • Contact: 苗明三,男,教授,博士;研究方向:主要从事中药药理教学与研究;E-mail:miaomingsan @163.com
  • About author:魏珍珍,女,硕士研究生;研究方向:中药药理学;E-mail:weizhenzhen08@126.com
  • Supported by:
    国家中医药管理局中医药标准化专项项目(No.2017-149-11),河南省产学研合作项目(No.182107000029)

摘要: 目的:探讨一种苏艾冰精油外用对小鼠抗缺氧能力的影响。方法:通过建立小鼠常压密闭缺氧模型、减压缺氧模型及异丙肾上腺素致小鼠缺氧模型,将苏艾冰精油涂抹于小鼠头面部、胸部,涂精油后放置于密闭环境中,记录小鼠的生存时间,以蒸馏水作为空白对照组,观察苏艾冰精油对小鼠抗缺氧能力的影响。结果:苏艾冰精油可显著延长常压密闭缺氧、减压缺氧、异丙肾上腺素缺氧小鼠的活存时间(P<0.01)。结论:苏艾冰精油可显著提高机体的耐缺氧能力。

关键词: 苏艾冰精油, 缺氧模型, 异丙肾上腺素, 芳香疗法

Abstract:

Objective:To investigate the effect of Suaibing essential oil on the antihypoxia ability of mice. Methods:Through the establishment of mice hypoxia model under
normal pressure,hypoxia model under reduced pressure and mice hypoxia model induced by isoproterenol,Suaibing essential oil was applied to the head,face and chest of mice. After being applied with essential oil,the mice were placed in a closed environment. The survival time of mice was recorded,and distilled water was used as a blank control group to observe the effect of SuAibing essential oil on anti-hypoxia ability of mice. Results:The experimental results show that Suaibing essential oil can significantly prolong the survival time of normal pressure sealed hypoxia,hypobaric hypoxia,and isoproterenol hypoxic mice(P<0.01). Conclusion:Suaibing essential oil can significantly improve the body’s hypoxia tolerance.

Key words: Suaibing essential oil, hypoxia model, isoproterenol, aromatic therapy

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