神经药理学报

神经药理学报 ›› 2023, Vol. 13 ›› Issue (5): 48-.DOI: 10.3969/j.issn.2095-1396.2023.05.009

• 研究论文 • 上一篇    下一篇

以顽固性呕吐起病的视神经脊髓炎谱系疾病2例并文献复习

唐晓婷，彭敦煌，房太勇   

  1. 福建医科大学附属第二医院消化内科，泉州，362000，中国
  • 出版日期:2023-10-26 发布日期:2024-05-09
  • 通讯作者: 房太勇，主任医师，学士；研究方向：消化道肿瘤基础与临床，非酒精性脂肪肝基础与临床
  • 作者简介:唐晓婷，主治医师，硕士研究生；研究方向：消化系统肿瘤、胃肠动力方向；E-mail：tingting6989@163.com

Two Cases of Neuromyelitis Optica Spectrum Disease with Refractory Vomiting As the Initial Symptom and Literature Review

TANG Xiao-ting, PENG Dun-huang, FANG Tai-yong   

  1. Department of Gastroenterology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, 362000, China
  • Online:2023-10-26 Published:2024-05-09
  • Contact: 房太勇，主任医师，学士；研究方向：消化道肿瘤基础与临床，非酒精性脂肪肝基础与临床
  • About author:唐晓婷，主治医师，硕士研究生；研究方向：消化系统肿瘤、胃肠动力方向；E-mail：tingting6989@163.com

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摘要：

视神经脊髓炎谱系疾病（neuromyelitis optica spectrum disorder, NMOSD）是一种少见的免疫介导的中枢神经系统疾病。长节段脊髓炎（＞3个椎体）、严重视神经炎和/或顽固性呕吐和呃逆极后区综合征(area postrema syndrome, APS)是该病的典型表现。其中有些病例以顽固性恶心、呕吐、呃逆为唯一的首发表现，早期易误诊、漏诊, 造成诊疗延误。本文报道2例以顽固性恶心、呕吐、呃逆起病的视神经脊髓炎谱系疾病，以期为该类病例的及早正确诊治提供启示。

关键词: 视神经脊髓炎, 视神经脊髓炎谱系疾病, 呕吐, 极后区综合征

Abstract:

Neuromyelitis optica spectrum disorder (NMOSD) is a rare immune-mediated central nervous system disease. Long-segment myelitis (>3 vertebrae), severe optic neuritis and/or intractable vomiting and hiccups (Area postrema syndrome, APS) are typical manifestations of the disease. Some cases with intractable nausea, vomiting, hiccups as the only initial symptom, result in early misdiagnosis and missed diagnosis, which delayed correct diagnosis and treatment. This article reports 2 cases of neuromyelitis optica spectrum disorders with intractable nausea, vomiting and hiccups as the initial symptom, in order to provide inspiration for the early and correct diagnosis and treatment of this disease.

Key words: Department of Gastroenterology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, 362000, China