神经药理学报

神经药理学报 ›› 2023, Vol. 13 ›› Issue (5): 52-.DOI: 10.3969/j.issn.2095-1396.2023.05.010

• 综述 • 上一篇    下一篇

生物样品的预处理技术研究进展

尤斯涵，殷宏艳，杨宋蕊，刘鑫淼，郭春燕   

  1. 河北北方学院药学院，河北省神经药理学重点实验室，张家口，075000，中国
  • 出版日期:2023-10-26 发布日期:2024-05-09
  • 通讯作者: 郭春燕，教授，硕士生导师；研究方向：体内药物分析和靶向药物分析；E-mail：guochy0311@163.com
  • 作者简介:尤斯涵，研究方向：网络药理学；E-mail: 478032008@qq.com

Advance in Pretreatment Techniques for Biological Samples

YOU Si-han, YIN Hong-yan, YANG Song-rui, LIU Xin-miao, GUO Chun-yan   

  1. Department of Pharmacy, Hebei North University, Hebei Key Laboratory of Neuropharmacology, Zhangjiakou, 075000, China
  • Online:2023-10-26 Published:2024-05-09
  • Contact: 郭春燕，教授，硕士生导师；研究方向：体内药物分析和靶向药物分析；E-mail：guochy0311@163.com
  • About author:尤斯涵，研究方向：网络药理学；E-mail: 478032008@qq.com

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摘要：

基于生物样品具有药物种类繁多、理化性质各异、生物介质组分复杂的特点，生物样品的预处理产生了多种技术和方法。基于以上背景，该文综述了近年来在体内药物分子中生物样品的预处理方法，以期为不同生物样品的预处理提供参考。

关键词:

生物样品, 预处理, 体内药物分析

Abstract:

Due to the diverse types of drugs, diverse physicochemical properties, and complex composition of biological media in biological samples, various technologies and methods have emerged for the pre-treatment of biological samples. Based on the above background, this article reviews the pre-treatment methods of biological samples in vivo drug molecules in recent years, with the aim of providing reference for the pre-treatment of different biological samples.

Key words: biological samples, pretreatment, in vivo drug analysis