神经药理学报

神经药理学报 ›› 2022, Vol. 12 ›› Issue (2): 47-.DOI: 10.3969/j.issn.2095-1396.2022.02.009

• 专题论著 • 上一篇    下一篇

偏头痛合并卵圆孔未闭的研究进展

赵博，禹爱梅，邹玉安   

  1. 1 河北北方学院研究生学院，张家口，075000，中国  2 河北北方学院附属第一医院神经内科，张家口，075000，中国
  • 出版日期:2022-04-26 发布日期:2022-04-26
  • 通讯作者: 邹玉安，主任医师，硕士研究生导师；E-mail：baiyitiansho@163.com
  • 作者简介:赵博，在读研究生；研究方向：神经病学；E-mail：18131374605@163.com

Research Progress in Migraine Combined with Patent Oval Foramen

ZHAO Bo，YU Ai-mei，ZOU Yu-an   

  1. 1. Graduate School of Hebei North University，Zhangjiakou，075000，China  2. Department of Neurology，The First Affiliated Hospital of Hebei North University，Zhangjiakou，075000，China
  • Online:2022-04-26 Published:2022-04-26

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摘要：

偏头痛是致残性的一种慢性神经血管疾病，其以严重的偏侧搏动样头痛发作为特征。偏头痛发作时疼 痛剧烈，其发作时会导致绝大部分日常生活活动及工作不能继续正常进行，生产力显着下降，医疗相关成本大幅 增加。偏头痛在世界上最常见的疾病中排名第三位（排在龋齿和紧张性头痛之后），疾病所致伤残排第八位，发病 率高，疾病负担重，影响范围广，给患者的生活质量产生显著的不利影响。

关键词: 偏头痛, 卵圆孔未闭, 右向左分流, 降钙素原相关基因肽, P 物质, 血小板

Abstract:

Migraine is a disabling chronic neurovascular disease characterized by severe hemiplegic headache attacks. Migraine attacks are intensely painful，and when they occur， most activities of daily living and work can no longer be carried out normally，productivity is significantly reduced，and healthcare-related costs are significantly increased. Migraine ranks third among the most common diseases in the world（after dental caries and tension headaches）， and ranks eighth in disability due to disease，with high morbidity，high disease burden，and wide impact. Significant adverse effects on the patient's quality of life.

Key words: migraine, patent oval foramen, right to left shunt, calcitonin gene related peptid, substance-P, platelet

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