神经药理学报 ›› 2014, Vol. 4 ›› Issue (5): 55-64.

• 综述 • 上一篇    

丹参酮ⅡA的药理作用及治疗应用研究进展

梅艳飞,  张丹参   

  1. 1. 河北北方学院药学系,张家口,075000,中国
    2. 河北科技大学,石家庄,050018,中国
  • 出版日期:2014-10-26 发布日期:2015-01-20
  • 通讯作者: 张丹参,女,教授,博士生导师;研究方向:神经药理学;Tel:+86-0311-81668016,E-mail:zhangds2011@126.com
  • 作者简介:梅艳飞,女,硕士研究生;研究方向:神经药理学;E-mail:myf_1990421@163.com

Pharmacological Actions and Therapeutic Applications of Tanshinone ⅡA

MEI Yan-fei, ZHANG Dan-shen   

  1. 1 Department of  Pharmancy, Hebei North University, Zhangjiakou, 075000, China 2 Hebei University Of Science and Technology, Shijiazhuang, 050018, China
  • Online:2014-10-26 Published:2015-01-20
  • Contact: 张丹参,女,教授,博士生导师;研究方向:神经药理学;Tel:+86-0311-81668016,E-mail:zhangds2011@126.com
  • About author:梅艳飞,女,硕士研究生;研究方向:神经药理学;E-mail:myf_1990421@163.com

摘要: 丹参酮ⅡA是丹参中有效成分的一种,是发挥其药理活性的基础。丹参酮ⅡA具有增加冠状动脉血流量、改善心肌功能、降低血小板聚集等功能,在临床上广泛应用于心脑血管疾病的治疗。其抗肿瘤、抗氧化、抗炎以及抗菌抑菌等多种生物学活性也扩大了丹参酮ⅡA的应用范围,具有良好的应用前景。本文将对丹参酮ⅡA的药理作用以及临床应用的情况作一综述。

关键词: 丹参酮ⅡA, 药理作用, 治疗应用

Abstract: Tanshinone ⅡA, one of the mainly active ingredients from Salvia miltiorrhiza Bge, is the basis of its pharmacological activity. Tanshinone ⅡA can increase the coronary blood flow, improve the myocardial function, reduce platelet aggregation, etc, therefore it is widely used in clinical treatment of cardio-cerebral blood vessel diseases. Because tanshinone ⅡA has various biological activities, such as anti-tumor, antioxidant, anti-inflammatory and antibacterial, these actions could enlarge its range of applications. In this review, the pharmacological actions and clinical applications of tanshinone ⅡA was summarized.

Key words: tanshinone ⅡA, pharmacological actions, therapeutic applications

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