神经药理学报 ›› 2012, Vol. 2 ›› Issue (5): 5-7.

• 研究论文 • 上一篇    下一篇

58例儿童后颅窝肿瘤病例的回顾性分析

李奇峰, 江峰, 赵阳, 马杰   

  1. 上海交通大学医学院附属新华医院小儿神经外科,上海,200090,中国
  • 出版日期:2012-10-26 发布日期:2014-06-27
  • 通讯作者: 马杰,男,教授,博士生导师;研究方向:儿童脑肿瘤病因;Tel:+86-02125078999,E-mail:ht989@163.com
  • 作者简介:李奇峰,男,博士研究生;研究方向:儿童脑肿瘤的发病机制;Tel:+86-02125078999, E-mail:lqf989@163.com
  • 基金资助:

    上海市优秀学科带头人基金项目(No.09XD1403300)

A Retrospective Analysis of 58 Cases of Posterior Fossa Tumors in Children    

LI Qi-feng, JIANG Feng, ZHAO Yang, MA Jie   

  1. Department of Pediatric Neurosurgery Xinhua Hospital, Shanghai, 200092, China
  • Online:2012-10-26 Published:2014-06-27
  • Contact: 马杰,男,教授,博士生导师;研究方向:儿童脑肿瘤病因;Tel:+86-02125078999,E-mail:ht989@163.com
  • About author:李奇峰,男,博士研究生;研究方向:儿童脑肿瘤的发病机制;Tel:+86-02125078999, E-mail:lqf989@163.com
  • Supported by:

    上海市优秀学科带头人基金项目(No.09XD1403300)

摘要: 目的:分析儿童后颅窝肿瘤的临床特点及病理类型,探讨手术方式及外科治疗相关问题。方法:对58例行手术治疗的后颅窝肿瘤患者的临床资料进行回顾性分析。结果:儿童颅内肿瘤以男性多见,女性较少;肿瘤以髓母细胞瘤、室管膜瘤、星形细胞瘤较多,临床表现与患者年龄、肿瘤部位有关;第四脑室及小脑蚓部肿瘤主要采用枕下正中入路,小脑半球肿瘤主要采用旁正中入路或枕下正中入路,桥小脑角区肿瘤主要采用枕下乙状窦后入路。结论:手术切除为后颅窝肿瘤的主要治疗方法。根据肿瘤的发生部位及具体情况选择恰当的手术方式可以减少术后并发症的发生。如有残留辅以伽玛刀、x刀放射治疗;恶性肿瘤术后常需放疗、化疗。

关键词: 后颅窝肿瘤, 外科治疗, 并发症

Abstract: Objective: To analyze the clinical characteristics and pathological types of posterior fossa tumors in children, and discuss related problems about surgical methods and surgical treatment.Methods: Clinical data on 58 patients with posterior fossa after surgery were retrospectively analyzed. Results: Children with intracranial tumors were more common in male, less in female. The Pathological diagnoses of brain tumor included medulloblastoma, ependymoma and astrocytoma. Clinical manifestations were determined by age and location of the tumors. Surgical approaches included craniotomy through suboccipital opening via middle road for the fourth ventricle and cerebellar vermis tumors, paramedian opening for cerebelar hemisphere tumors, and retrosigmoid approach for cerebellopontine angle area tumors. . Conclusion: Surgical resection is the main treatment of posterior fossa tumors. Proper operation method based on tumor locations and the specific situations can reduce the occurrence of postoperative complications. Malignant tumors often need radiotherapy, and chemotherapy after surgery.