神经药理学报 ›› 2021, Vol. 11 ›› Issue (3): 25-32.DOI: 10.3969/j.issn.2095-1396.2021.03.006

• 专题论著 • 上一篇    下一篇

急性放射病防治药物的研究进展

王佳,尤斯涵,郭春燕   

  1. 1 河北北方学院药学系,张家口,075000,中国
    2 河北医科大学基础医学院,石家庄,050000,中国
  • 出版日期:2021-06-26 发布日期:2021-06-26
  • 通讯作者: 郭春燕,教授,硕士生导师;研究方向:体内药物分析和靶向药物分析;E-mail:guochy0311@163.com
  • 作者简介:王佳,硕士研究生;研究方向:离子通道与疾病

Research Progress on Drugs for Prevention and Treatment of Acute Radiation Syndrome

WANG Jia,YOU Si-han,GUO Chun-yan   

  1. 1 Departement of Pharmacy,Hebei North University,Zhangjiakou,075000,China
    2 School of Basic Medicine,Hebei Medical University,Shijiazhuang,075000,China
  • Online:2021-06-26 Published:2021-06-26

摘要:

急性放射病(acute radiation syndrome,ARS)是指机体在短时间内受到大剂量电离辐射照射后引起的全身性疾病,可分为骨髓型(1~10 Gy)、肠型(10~50 Gy)和脑型(>50 Gy)三种类型。ARS 主要表现为造血系统功能抑制和免疫功能受损。该文介绍了主要作用为恢复造血系统、增强免疫功能及改善并发症的急性放射病防治药物的研究进展。

关键词: 急性放射病, 防治药物, 造血系统, 免疫系统

Abstract:

Acute radiation syndrome (ARS) is a systemic disease caused by exposure to large doses of ionizing radiation in a short period of time. It can be divided into bone marrow type (1~10 Gy),intestinal type (10~50 Gy) and brain type (>50 Gy). ARS is mainly manifested as hematopoietic system inhibition and immune function impairment. This article introduces the research progress of drugs for the prevention and treatment of acute radiation syndrome with the main functions of restoring the hematopoietic system,enhancing immune function and improving complications.

Key words: acute radiation syndrome, prevention and treatment drugs, hematopoietic system, immune system

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