神经药理学报

神经药理学报 ›› 2021, Vol. 11 ›› Issue (3): 15-19.DOI: 10.3969/j.issn.2095-1396.2021.03.004

• 专题论著 • 上一篇    下一篇

单味中药提取物防治类风湿性关节炎机制探究

许飞，李学军   

  1. 1. 安徽凤阳县人民医院，凤阳，233100，中国
    2. 安徽中医药大学第二附属医院，合肥，230000，中国
  • 出版日期:2021-06-26 发布日期:2021-06-26
  • 作者简介:许飞，E-mail：786180189@qq.com

Study on the Mechanism of Single Chinese Medicine Extract in the Prevention and Treatment of Rheumatoid Arthritis

XU Fei，LI Xue-Jun   

  1. 1 The People’s Hospital of Fengyang County，Fengyang，233100，China
    2 The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine，Hefei，230000，China
  • Online:2021-06-26 Published:2021-06-26

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摘要：

类风湿性关节炎是一种病因未明的风湿科常见自身免疫性疾病，目前临床以非甾体类抗炎药、激素、免疫抑制剂等为主要治疗方案，症状虽改善迅速，但副作用较多（如胃肠道反应、肝肾功能损伤等），且易复发，限制患者后续治疗。因此，当务之急是寻找安全可靠、疗效明显的治疗药物。近年来，大量研究表明单味中药提取物在类风湿性关节炎防治方面具有明显优势，该文就单味中药提取物治疗类风湿性关节炎的作用机制展开综述，以期为类风湿性关节炎的实验研究及临床运用提供参考依据。

关键词: 类风湿性关节炎, 单味中药, 机制, 研究

Abstract:

Rheumatoid arthritis（RA） is a common autoimmunedisease in rheumatology department with unknown etiology.Currently，non steroidal anti-inflammatory drugs，hormones and immunosuppressants are the main treatment options in clinic.Although the symptoms improve rapidly，there are many side effects（such as gastrointestinal reactions，liver and kidney function damage，etc.），and it is easy to relapse，which limits the follow-up treatment of patients.Therefore，it is urgent to find safe and effective drugs.In recent years，a large number of studies have shown that single Chinese medicine extract has obvious advantages in the prevention and treatment of rheumatoid arthritis.This paper reviews the mechanism of single Chinese medicine extract in the treatment of rheumatoidarthritis，in order to provide reference for the experimental research and clinical application of rheumatoid arthritis.

Key words: rheumatoid arthritis, single traditional Chinese medicine, mechanism, research

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