神经药理学报

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含天麻中成药的应用与分析

刘慧娟,白明,苗明三   

  1. 河南中医药大学,郑州, 450000, 中国
  • 出版日期:2019-12-26 发布日期:2020-03-03
  • 通讯作者: 苗明三,男,教授,博士;研究方向:中药药理教学与研究; E-mail:miaomingsan @163.com
  • 作者简介:刘慧娟,女,研究生;研究方向:药理学; E-mail:liuhuijuan_n@126.com
  • 基金资助:
    国家重大新药创制项目(No.2017ZX09301071),国家国际合作基地(No.2016-15)

Application and Analysis of Chinese Patent Medicine Containing Gastrodia elata Blume

LIU Hui-juan,BAI ming,MIAO Ming-san   

  1. Henan University of Chinese Medicine,Zhengzhou,450000,China
  • Online:2019-12-26 Published:2020-03-03
  • Contact: 苗明三,男,教授,博士;研究方向:中药药理教学与研究; E-mail:miaomingsan @163.com
  • About author:刘慧娟,女,研究生;研究方向:药理学; E-mail:liuhuijuan_n@126.com
  • Supported by:
    国家重大新药创制项目(No.2017ZX09301071),国家国际合作基地(No.2016-15)

摘要:

天麻应用前景广泛,市场开发产品众多,其化学成分主要有酚类、有机酸类、甾醇类等,具有镇静镇痛、 降压抗血栓、抗癫痫的作用。天麻单药的活性成分的研究较多,但含天麻中成药应用的研究相对较少。该文通过 对 2015 版《中国药典》中所有含天麻的中成药的组成情况、应用形式、功能主治注意事项等进行归纳整理,对其 高频中药进行关联规则分析,挖掘天麻与其他中药的配伍方式,为开发含天麻新药提供指导,为临床使用含天麻 中成药提供参考。

关键词: 天麻, 中成药, 关联规则, 临床应用

Abstract:

Gastrodia elata has a wide range of applications and many market development products. Its chemical components mainly include phenols,organic acids,sterols and it has the effects of calming analgesia,antihypertensive,antithrombotic and antiepileptic. There are many studies on Gastrodia elata Blume monotherapy and active ingredients,but there are relatively few studies on the application of Chinese Patent Medicine containing Gastrodia elata Blume. Therefore, this article summarizes the composition,application forms,and functional indications of all Chinese-based medicines containing Gastrodia elata in the 2015 edition of the Chinese Pharmacopoeia,analyzes the association rules of high-frequency Chinese medicines,and explores the compatibility of Gastrodia elata with other traditional Chinese medicines. To provide guidance for the development of new drugs containing Gastrodia elata,and reference for the clinical use of Gastrodia elata-containing Chinese patent medicines.

Key words: Gastrodia elata Blume, chinese patent medicine, association rule, clinical application

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