神经药理学报

神经药理学报 ›› 2026, Vol. 16 ›› Issue (2): 58-.DOI: 10.3969/j.issn.2095-1396.2026.02.009

• 综述 • 上一篇    

红景天苷对消化系统恶性肿瘤研究进展

白晓晨，程永婷，闫伟东，王辰洋，费建东   

  1. 1. 河北北方学院附属第一医院胃肠外科，张家口，075000，中国 

    2. 河北北方学院附属第一医院麻醉科，张家口，075000，中国

  • 出版日期:2026-04-30 发布日期:2026-06-16
  • 通讯作者: 费建东，教授，主任医师，硕士研究生导师；研究方向：胃肠外科
  • 作者简介:白晓晨，在读硕士研究生；研究方向：普通外科

Research Progress of Salidroside on Digestive System Malignant Tumors

BAI Xiao-chen, CHENG Yong-ting, YAN Wei-dong, WANG Chen-yang, FEI Jian-dong   

  1. 1. Department of Gastrointestinal Surgery, the First Affiliated Hospital of Hebei North University, Zhangjiakou, 075000, China 

    2. Department of Anesthesiology, the First Affiliated Hospital of Hebei North University, Zhangjiakou, 075000, China

  • Online:2026-04-30 Published:2026-06-16

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摘要：

消化系统恶性肿瘤严重威胁人类健康，尽管医疗水平的上升，但癌症的死亡率仍居高不下。红景天苷 （salidroside）作为红景天类植物中提取的苯乙醇苷类化合物，具有较为显著的抗肿瘤作用，在消化系统恶性肿瘤 研究方面展现出潜在价值，目前研究聚焦于其抗肿瘤机制探索及临床应用前景评估。该综述将从抑制肿瘤细胞 增殖、阻滞周期进展、诱导凋亡、抑制肿瘤细胞的侵袭转移以及联合用药的抗肿瘤作用对红景天苷作用于恶性肿 瘤的机制进行探讨。

关键词: 红景天苷, 消化系统恶性肿瘤, 抗肿瘤机制, 细胞凋亡

Abstract:

Malignant tumors of the digestive system pose a serious threat to human health. Despite advances in medical technology, the mortality rate of cancer remains high. Salidroside, a phenylethanol glycoside compound extracted from Rhodiola plants, exhibits significant antitumor effects and demonstrates potential value in the research of digestive system malignancies. Current studies focus on exploring its anti-tumor mechanisms and evaluating its clinical application prospects. This review will discuss the mechanisms by which salidroside acts on malignant tumors, including: inhibiting tumor cell proliferation, arresting cell cycle progression, inducing apoptosis, suppressing tumor cell invasion and metastasis, and its anti-tumor effects in combination therapies.

Key words: salidroside, digestive system malignancies, antitumor mechanism, apoptosis

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