睡眠剥夺对学习记忆及中枢神经系统相关分子的影响

摘要/Abstract

摘要： 当代社会的各种主客观因素，使得睡眠剥夺的发生成为常态，其对人们生活的不良影响正日益突出，已日渐成为国内外的研究热点。本文回顾了近年来睡眠剥夺研究的相关文献，概要了其研究方法及其对学习记忆的影响，着重分析了睡眠剥夺对中枢神经系统相关基因和蛋白变化的影响。

关键词: 睡眠剥夺, 中枢神经系统, 基因, 蛋白

Abstract: Sleep deprivation(SD), a very common phenomenon in modern society, has been becoming one of the most significant medical problems because of its detrimental effects on human’s health. This paper reviewed the SD related studies in recent years and gave a brief summary on the research methods of SD and the effects of SD on learning and memory, with a particular focus on the changes of genes and proteins affected by SD in central nervous system.

Key words: sleep deprivation(SD), central nervous system, gene, protein

郭兴道李炜张癸荣张丹参程鹏. 睡眠剥夺对学习记忆及中枢神经系统相关分子的影响[J]. 神经药理学报, 2014, 4(1): 34-51.

GUO Xing-dao，LI Wei，ZHANG Guirong，ZHANG Dan-shen，CHENG Peng. Effects of Sleep Deprivation on Learning and Memory and the Molecules In Central Nervous System[J]. Acta Neuropharmacologica, 2014, 4(1): 34-51.

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