神经药理学报 ›› 2025, Vol. 15 ›› Issue (6): 36-.DOI: 10.3969/j.issn.2095-1396.2025.06.005

• 研究论文 • 上一篇    下一篇

千金苇茎汤联合针灸对痰热壅肺型老年吸入性肺炎患者疗效及炎症指标、预后的影响

严敏,谭韬   

  1. 1. 贵州中医药大学第二临床医学院,贵阳,550003,中国 

    2. 贵州中医药大学第二附属医院,贵阳,550003,中国

  • 出版日期:2025-12-26 发布日期:2026-03-30
  • 通讯作者: 谭韬,副主任医师,硕士研究生;研究方向:呼吸系统疾病防治
  • 作者简介:严敏,住院医师,硕士研究生在读;研究方向:呼吸系统疾病防治
  • 基金资助:
    贵州省中医药管理局中医药、民族医药科学技术研究项目(No.QZYY2013-59)

Effects of Qianjin Weijing Decoction Combined with Acupuncture on Curative Efficacy, Inflammatory Markers, and Prognosis in Elderly Patients with Aspiration Pneumonia of Phlegm-Heat Obstructing the Lung Type

YAN Min, TAN Tao   

  1. 1. The Second Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang, 550003, China 

    2. The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, 550003, China

  • Online:2025-12-26 Published:2026-03-30

摘要:

目的:探讨千金苇茎汤联合针灸治疗痰热壅肺证老年吸入性肺炎的临床疗效及对炎症指标、预后的影 响。方法:选取2022 年4 月至2023 年6 月贵州中医药大学第二附属医院收治的105 例老年吸入性肺炎患者随 机分为对照组(n=52)和联合组(n=53)。两组均给予纤支镜冲洗吸痰、防治食管胃反流、口腔清洁护理、营养支持 等治疗,对照组在此基础上给予注射头孢他啶治疗,联合组在对照组处理基础上给予千金苇茎汤和针灸治疗。比 较两组的治疗效果、C 反应蛋白(C-reactive protein,CRP)、降钙素原(procalcitonin,PCT)、血气指标、APACHE II 评分、CPIS 评分、一年内复发次数、肺部啰音消失时间、咳嗽持续时间、血痰培养情况。结果:治疗后,联合组总 有效率高于对照组(χ2=11.165,P<0.05)。治疗后,联合组CRP、PCT、动脉血中二氧化碳分压(partial pressure of carbon dioxide,PaCO2)、APACHE II 评分、CPIS 评分低于对照组,动脉血氧分压(partial pressure of oxygen,PaO2) 高于对照组(P<0.05)。治疗后,联合组一年内复发次数、肺部啰音消失时间、咳嗽持续时间低于对照组(P<0.05)。 治疗后,联合组总菌株合计低于对照组(χ2=9.535,P<0.05)。结论:在标准抗生素治疗基础上,千金苇茎汤联合针 灸治疗老年吸入性肺炎,能更有效地改善氧合、减轻炎症反应、缓解临床症状、降低复发率。

关键词: 千金苇茎汤, 针灸, 老年吸入性肺炎, 痰热壅肺型, 血气, 血痰培养

Abstract:

Objective: To investigate the clinical efficacy of Qianjin Weijing Decoction combined with acupuncture in treating elderly patients with aspiration pneumonia presenting with the phlegm-heat obstructing the lung syndrome, and to evaluate its impact on inflammatory indicators and prognosis. Methods: A total of 105 elderly patients with aspiration pneumonia admitted to our hospital between April 2022 and June 2023 were selected and randomly assigned to a control group (n=52) and a combination group (n=53). Both groups received conventional treatments, including fiberoptic bronchoscopic lavage and sputum suction, prevention and management of gastroesophageal reflux, oral care, and nutritional support. The control group received additional treatment with intravenous ceftazidime. The combination group received Qianjin Weijing Decoction and acupuncture in addition to the treatments administered to the control group. The therapeutic efficacy, levels of C-reactive protein (CRP) and procalcitonin (PCT), blood gas parameters, APACHE II scores, Clinical Pulmonary Infection Score (CPIS), number of recurrences within one year, time to disappearance of pulmonary rales, duration of cough, and results of blood and sputum cultures were compared between the two groups. Results: After treatment, the total effective rate was significantly higher in the combination group than in the control group (χ2=11.165, P<0.05). Post-treatment, the combination group exhibited significantly lower levels of CRP, PCT, arterial partial pressure of carbon dioxide (PaCO₂), APACHE II scores, and CPIS scores, and a significantly higher arterial partial pressure of oxygen (PaO₂) compared to the control group (P<0.05). Furthermore, the number of recurrences within one year, the time to disappearance of pulmonary rales, and the duration of cough were significantly lower in the combination group than in the control group (P<0.05). The total number of bacterial strains identified in blood and sputum cultures post-treatment was also significantly lower in the combination group (χ²=9.535, P<0.05). Conclusion: For elderly patients with aspiration pneumonia, the addition of Qianjin Weijing Decoction and acupuncture to standard antibiotic therapy can more effectively improve oxygenation, alleviate the inflammatory response, relieve clinical symptoms, and reduce the recurrence rate.

Key words: qianjin weijing decoction, acupuncture, elderly aspiration pneumonia, phlegm-heat obstructing the lung type, blood gas analysis, blood and sputum culture

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