神经药理学报

神经药理学报 ›› 2022, Vol. 12 ›› Issue (1): 30-34.DOI: 10.3969/j.issn.2095-1396.2022.01.005

• 研究论文 • 上一篇    下一篇

连朴饮加减治疗湿热中阻型反流性食管炎临床疗效观察

徐树春，张元明   

  1. 1. 北京工业大学医院中医科，北京，100124，中国  2. 北京市昌平区中医医院中医科，北京，102200，中国
  • 出版日期:2022-02-26 发布日期:2023-08-30
  • 作者简介:徐树春，主治医师（中医）；研究方向：内科杂症；E - mail：18911631218@189.cn

Clinical Efficacy of Modified Lianpu Yin in the Treatment of Moderate Resistance Type Reflux Esophagitis Caused by Dampness and Heat

XU Shu - chun ，ZHANG Yuan - ming   

  1. 1. Department of Traditional Chinese Medicine，Beijing University of Technology Hospital，Beijing，100124， China  2. Department of Traditional Chinese Medicine，Changping District Traditional Chinese Medicine Hospital， Beijing，102200，China
  • Online:2022-02-26 Published:2023-08-30

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摘要：

目的：探讨连朴饮加减治疗湿热中阻型反流性食管炎临床疗效。方法：选取2020 - 3 ~ 2022 - 3 月北京市 昌平区中医医院收治的104 例湿热中阻型反流性食管炎患者，按随机数字表法分为对照组与研究组各52 例，对 照组应用兰索拉唑治疗，研究组应用连朴饮加减治疗，4 周1 疗程。治疗1 疗程后观察患者临床疗效、炎性因子 水平、免疫指标、生活质量及不良反应情况。结果：治疗1 疗程后，研究组临床疗效、生活质量、免疫功能水平优 于对照组（P<0.05）；炎性因子水平、不良反应率低于对照组（P<0.05）。结论：连朴饮加减治疗湿热中阻型反流性 食管炎可有效改善患者临床症状，降低不良反应发生率，改善患者机体炎性因子及免疫指标，提高患者整体生活质量。

关键词: 湿热中阻, 反流性食管炎, 兰索拉唑, 连朴饮

Abstract:

Objective：To explore the clinical efficacy of Lianpu Yin in the treatment of moderate resistance type reflux esophagitis caused by dampness and heat. Methods：104 patients with moderate obstructive reflux esophagitis of damp heat type admitted from March 2020 to March 2022 were randomly divided into a control group and a study group，with 52 patients in each group. The control group was treated with Lansoprazole，while the study group was treated with Lianpu Yin，with a course of treatment lasting for 4 weeks. Results：After one course of treatment，observe the patient’s clinical efficacy，inflammatory factor levels，immune indicators， quality of life，and adverse reactions. After one course of treatment，the clinical efficacy，quality of life，and immune function level of the study group were better than those of the control group （P<0.05）；The levels of inflammatory factors and adverse reaction rates were lower in the control group （P<0.05）. Conclusion：Modified Lianpu Yin can effectively improve clinical symptoms， reduce the incidence of adverse reactions，improve inflammatory factors and immune indicators in patients with moderate resistance to dampness and heat reflux esophagitis，and improve their overall quality of life.

Key words: damp heat resistance, reflux esophagitis, lansoprazole, lianpu drink