内皮素在妇科疾病中发病作用机制的研究进展

doi:10.3969/j.issn.2095-1396.2019.06.007

神经药理学报

内皮素在妇科疾病中发病作用机制的研究进展

王迪，成秀梅，任威威，等

河北中医学院，石家庄，050091，中国

出版日期:2019-12-26 发布日期:2020-03-03
通讯作者: 成秀梅，女，教授，博士研究生导师；研究方向：月经病寒证的实质研究
作者简介:王迪，女，博士研究生；研究方向：月经病寒证的实质研究
基金资助:
河北省研究生创新基金项目（No：CXZZBS2018156），河北省教育厅重点项目（No：ZD2018035），河北中医学院科技能力提升项目（No：KTZ 2019003）

Research Progress of Endothelin in the Pathogenesis of Gynecological Diseases

WANG Di，CHENG Xiu-mei，REN Wei-wei, et al

Hebei University of Chinese Medicine，Shijiazhuang，050091，China

Online:2019-12-26 Published:2020-03-03
Contact: 成秀梅，女，教授，博士研究生导师；研究方向：月经病寒证的实质研究
About author:王迪，女，博士研究生；研究方向：月经病寒证的实质研究
Supported by:
河北省研究生创新基金项目（No：CXZZBS2018156），河北省教育厅重点项目（No：ZD2018035），河北中医学院科技能力提升项目（No：KTZ 2019003）

摘要/Abstract

摘要： 内皮素（endothelin，ET）是迄今为止发现的作用最强、持续时间最久，具有局部调节和收缩作用的血管活性多肽。ET 亦对生殖激素分泌、生殖器官生理功能、肌肉收缩和细胞有丝分裂具有调节作用，在哺乳动物生殖过程中担任重要角色。现对内皮素在妇科疾病发病机制中的作用做一综述。

关键词: 内皮素, 生物学特性, 妇科疾病

Abstract:

Endothelin（ET）is one of the most potent and long-lasting vasoactive polypeptides with local regulation and contraction. ET can also regulate the secretion of reproductive hormones，physiological function of reproductive organs，muscle contraction and cell mitosis. It plays an important role in the reproductive process of mammals. This article reviews the role of endothelin in the pathogenesis of gynecological diseases.

Key words: endothelin, biological characteristics, gynecological diseases

中图分类号:

R271

王迪，成秀梅，任威威，等. 内皮素在妇科疾病中发病作用机制的研究进展[J]. 神经药理学报, DOI: 10.3969/j.issn.2095-1396.2019.06.007.

WANG Di，CHENG Xiu-mei，REN Wei-wei, et al. Research Progress of Endothelin in the Pathogenesis of Gynecological Diseases[J]. Acta Neuropharmacologica, DOI: 10.3969/j.issn.2095-1396.2019.06.007.

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内皮素在妇科疾病中发病作用机制的研究进展

Research Progress of Endothelin in the Pathogenesis of Gynecological Diseases

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