神经药理学报

神经药理学报 ›› 2023, Vol. 13 ›› Issue (1): 21-.DOI: 10.3969/j.issn.2095-1396.2023.01.004

• 研究论文 • 上一篇    下一篇

肾衰宁片联合甘精胰岛素治疗糖尿病肾病的临床疗效及对血糖、肾功能指标的影响

宁超   

  1. 德兴市中医院，德兴，334200，中国
  • 出版日期:2023-02-26 发布日期:2023-11-29
  • 作者简介:宁超，主治医师；E-mail:251060772@qq.com

Clinical Efficacy of Shenshuaining Tablet Combined with Insulin Glargine in The Treatment of Diabetic Nephropathy and Its Influence on Blood Glucose and Renal Function Indexes

NING chao   

  1. Dexing Hospital of Traditional Chinese Medicine, Dexing, 334200, China
  • Online:2023-02-26 Published:2023-11-29

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摘要： 目的：探讨在糖尿病肾病（diabetic nephropathy, DN）治疗中联合肾衰宁片和甘精胰岛素的效用。方法：回顾调查研究，将2019年1月～2020年12月就诊于德兴市中医院肾内科的70例DN患者按照不同治疗方式分组，各35例。对照组以基础降糖和甘精胰岛素治疗，观察组在其基础上同时联合肾衰宁片治疗，比较两组治疗效果及相关血清指标变化。结果：治疗后比较，观察组Scr、BUN和24h-pro水平低于对照组（P＜0.05）；两组治疗后 2h-PG、FBG和HbA1c水平较治疗前明显降低（P＜0.05）；观察组治疗总有效率高于对照组（P＜0.05）。结论：在DN治疗中联合肾衰宁片和甘精胰岛素可以改善患者肾功能，降低血糖水平，值得应用。

关键词: 糖尿病肾病, 肾衰宁片, 甘精胰岛素, 血糖, 肾功能

Abstract:

Objective: To investigate the effect of Shenshuaining tablet combined with insulin glargine in the treatment of diabetic nephropathy (DN). Methods: A retrospective study was conducted, and 70 patients with DN admitted to the Department of Nephrology of our hospital from January 2019 to December 2020 were divided into 35 cases each according to different treatment methods. The control group was treated with basic hypoglycemia and insulin glargine, and the observation group was treated with Shenshuaining tablet at the same time. The therapeutic effect and the changes of related serum indexes were compared between the two groups. Results: After treatment, Scr, BUN and 24h-pro levels in observation group were lower than those in control group (P < 0.05). The levels of 2h-PG, FBG and HbA1c in both groups were significantly lower after treatment than before treatment (P < 0.05); The total effective rate of observation group was higher than that of control group (P < 0.05). Conclusion: The combination of Shenshuaining tablet and insulin glargine in the treatment of DN can improve renal function and reduce blood glucose level in patients, which is worthy of application.

Key words: diabetic nephropathy, shenshuaining tablet, insulin glargine, blood sugar, renal function